Shilpa Medicare Limited
Precision Medicine
Innovation

Custom Peptide Synthesis — Built Around Your Molecule, Your Timeline

Advanced pharmaceutical solutions

Targeted • Precise • Effective

From milligrams for early research to kilograms for clinical supply — complex molecules delivered with flexibility and speed.

Peptides
Custom synthesis
Polymers
Drug delivery
ADCs
Targeted therapy
Custom Peptide Synthesis — Built Around Your Molecule, Your Timeline
1000+
Peptides Synthesized
50+
Polymer Types
200+
ADC Projects
99.5%
Purity Standard

Custom Peptide Synthesis — Built Around Your Molecule, Your Timeline

Whether you need milligrams for early research or kilograms for clinical supply, our custom peptide synthesis services adapt to your program. From simple linear sequences to highly modified peptidomimetics, our scientific and manufacturing teams deliver complex molecules with the flexibility and speed that modern peptide R&D demands.

Core Capabilities

Custom Synthesis

Linear and cyclic peptides, complex constructs, peptidomimetics, conjugated peptides, and peptide libraries

Scale Capabilities

Research, preclinical, clinical, and commercial manufacturing scale

Technical Expertise

Complex peptide synthesis, process optimization, route scouting, and technology transfer support

Analytical & Purification

Advanced characterization, high-purity isolation, RP-HPLC purification, and LC-MS/MS support

Operational Flexibility

Fast turnaround timelines, flexible batch sizes, dedicated project management, customized support

Advanced Peptide Modifications & Peptidomimetics

Comprehensive peptide engineering capabilities — from simple modifications through full peptidomimetic design.

Modification Capabilities

  • • Linear peptides
  • • Branched peptides
  • • Peptides up to 80 amino acids
  • • 50+ branch architectures
  • • Peptide libraries
  • • Complex peptide constructs

Terminal Modifications

  • • Amidation
  • • Alcohols & aldehydes
  • • Esters & thioesters
  • • PEGylation
  • • Lipid incorporation
  • • Acetylation & acylation
  • • Biotinylation
  • • Phosphorylation
  • • Sulfation
  • • Glycosylation

Cyclization & Backbone Modifications

  • • Single and multiple disulfide bridges
  • • Head-to-tail cyclization
  • • Side-chain cyclization
  • • Hydrocarbon-stapled peptides
  • • CLICK chemistry
  • • D-enantiomers
  • • N-methyl amino acids
  • • Unusual amino acids
  • • β-amino acids
  • • Peptidomimetics

Process Development & Advanced Purification

Process Development & Scale-Up

  • • Multi-gram to multi-kilogram scale manufacturing
  • • Cost-effective, scalable cGMP production
  • • Dedicated process optimization teams
  • • Robust technology transfer support
  • • Efficient scale-up strategies

Advanced Purification Technologies

  • • RP-HPLC
  • • Nano-filtration
  • • Ultra-filtration
  • • High-purity peptide isolation
  • • cGMP / GMP-like purification operations

Comprehensive Analytical & Structural Characterization

Analytical Techniques

  • • LC-MS/MS (QTOF)
  • • HPLC / UPLC
  • • GC (residual solvents)
  • • Amino acid analysis
  • • Peptide mapping
  • • N & C terminal confirmation
  • • Oligomer / monomer profiling

Structural Characterization

  • • NMR (1H, 13C, 2D – COSY, HSQC)
  • • Circular Dichroism (Far UV, Near UV)
  • • cIEF (Isoform & pI)
  • • SEC-MALS
  • • SEC-HPLC
  • • SV-AUC

Discuss Your Custom Peptide Requirements

Discuss your custom peptide development requirements with our technical experts.

Contact Us